Proposal Assessment b
: Novelty Seeking
suggests that the complex clinical phenotype defined by
personality test scales is unsuitable for genetic analysis.
They propose to identify a number of intermediate phenotypes
) associated with NS. Candidate endophenotypes
identified by the team range from specific learning deficits to
distinctive neuroimaging results. The expectation is that the
endophenotypes will prove more genetically uniform - perhaps making
it possible to reanalyze data from earlier family studies of NS -
and that it will prove possible to construct transgenic animal
models of the endophenotypes.
Please assess this proposal, using a scale from 1 to 5.
1. Highest Priority
5. Lowest Priority
6. Skip Item